What is the primary action of sucralfate that a nurse should explain to a client with peptic ulcer disease?

Sucralfate primarily acts by forming a protective barrier over ulcers. When sucralfate is administered, it interacts with gastric acid to create a viscid, adhesive substance that binds to the surface of ulcers and erosions in the gastrointestinal tract. This protective barrier serves to shield the ulcer from further irritation by stomach acids and digestive enzymes, facilitating healing and providing a safe environment for tissue repair.

This mechanism of action is particularly relevant for patients suffering from peptic ulcers, as it directly addresses the physical damage to the mucosal lining. By providing this barrier, sucralfate helps alleviate symptoms and promote healing, distinguishing it from other agents that may reduce acid production or neutralize acid in the stomach.

Other options, while related to ulcer treatment, do not accurately describe sucralfate's primary function. For instance, decreasing stomach acid secretion and neutralizing acids are actions characteristic of antacids or proton pump inhibitors, while treating ulcers by eradicating H. pylori involves the use of antibiotics or specific anti-infective therapies rather than a protective agent like sucralfate.